Found 55 datasets matching "screening and prioritization".
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Extents of impact, as measured by NMR spectroscopy, on the Zebrafish liver cell endogenous metabolite profiles resulting from exposure to the 38 stream waters, along with numbers of anthropogenic...
Search relevance: 104.78 | Views last month: 3 -
Data from which figures and table in "A Model for Risk-Based Screening and Prioritization of Human Exposure to Chemicals from Near-Field Sources" were constructed. This dataset is associated...
Search relevance: 54.94 | Views last month: 3 -
Prioritization of environmental contaminants can be aided by detecting glucuronidated biotransformation products in fish using untargeted mass spectrometry-based metabolomics. This dataset is...
Search relevance: 43.53 | Views last month: 0 -
List of chemicals used for model evaluation, their MW, log KOW, and references for the original data source(s), the review(s) the data was collected from, and reference for log KOW as cited in the...
Search relevance: 43.49 | Views last month: 0 -
Prioritization of chemicals was performed on two Areas of Concerns in the Great Lakes An integrated risk surveillance and monitoring approach was applied Bio-effect prediction methodologies were...
Search relevance: 40.96 | Views last month: 1 -
The datafile contains data associated with analytical chemistry, fish gene expression, in vitro bioassays, chemical prioritization, and Attagene data for surface water monitoring and caged fish...
Search relevance: 40.91 | Views last month: 1 -
Predictive models and frameworks for linking inhibition of the enzyme aromatase, as measured in non-animal high throughput screening assays, to adverse effects on reproduction in fish have been...
Search relevance: 40.91 | Views last month: 0 -
Final Data SeqAPASS v3.0.zip contains datasets from Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool versions 3.0 for all 497 proteins evaluated using Level 1 (primary...
Search relevance: 40.63 | Views last month: 0 -
Disruption of thyroid hormone signaling is a form of endocrine disruption that is of concern to both human health and ecosystems. Research is being conducted to define the biological targets...
Search relevance: 40.31 | Views last month: 0 -
Fathead minnows (Pimephales promelas) were exposed to 100 ug/L indomethacin, 200 ug/L ibuprofen, or 20 ug/L celecoxib for 96 h. Effects on cycloxygenase enzyme activity in ovary, prostaglandin...
Search relevance: 40.18 | Views last month: 2 -
In vitro biological activity data from a extracts of a nationwide survey of US streams. This dataset is associated with the following publication: Blackwell, B., G. Ankley, P. Bradley, K. Houck,...
Search relevance: 40.18 | Views last month: 0 -
Concentrations of 127 organic chemicals measured in water samples collected from five locations in proximity to two municipal wastewater treatment plants in the St. Croix River basin, MN and WI,...
Search relevance: 40.18 | Views last month: 0 -
Toward an AOP Network-based tiered testing strategy for the assessment of thyroid hormone disruption
No novel data were reported in association with this product. This dataset is not publicly accessible because: The associated publication is a review/forum-type article. No novel scientific data...
Search relevance: 39.74 | Views last month: 0 -
Contaminant data from bald eagles in the Upper-Midwest of the US. Dataset contains five tables in total including details of sample collection locations, organic contaminant data, and...
Search relevance: 39.74 | Views last month: 0 -
Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
Search relevance: 39.58 | Views last month: 1 -
To better understand the transport of neonicotinoid insecticides into the Great Lakes, monthly samples (October 2015-September 2016) were collected from 10 tributaries to the Great Lakes, USA. At...
Search relevance: 39.16 | Views last month: 4 -
The present study describes pilot testing of a high throughput compatible transcriptomics assay with larval fathead minnows. One day post hatch fathead minnows were exposed to eleven different...
Search relevance: 39.14 | Views last month: 0 -
This dataset presents the full hepatic transcriptomes of fathead minnows (Pimephales promelas) caged for four days at multiple sites within the Milwaukee Estuary area of concern and additional...
Search relevance: 39.14 | Views last month: 0 -
The dataset includes survival of control, control injected, and CRISPR/Cas9 injected embryos as well as percent efficiency of insertion/deletion mutation formation for the three different CRISPR...
Search relevance: 38.88 | Views last month: 3 -
This research was designed to evaluate whether a biologically-based computational model aligned with an adverse outcome pathway (AOP) could effectively predict animal (in vivo) responses to...
Search relevance: 38.88 | Views last month: 2
