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NSDUH 2021 Sample Design Report

Published by Substance Abuse and Mental Health Services Administration | U.S. Department of Health & Human Services | Metadata Last Checked: September 06, 2025 | Last Modified: 2025-09-06
This report describes the sample design for the 2021 National Survey on Drug Use and Health (NSDUH). It describes the target population and the five stages of sample selection, including the impact of coronavirus disease 2019 (COVID-19) pandemic. It also includes information on sample weighting and variance estimation procedures for the 2021 NSDUH.Chapter 1 introduces the report, describes the target population, provides a general overview of the 2021 NSDUH sample design, and summarizes the impact of the COVID-19 pandemic on the 2021 NSDUH. Chapter 2 summarizes the 2014 through 2022 coordinated design, while Chapter 3 discusses the first three stages of selection in greater detail. Chapter 4 describes the fourth and fifth stages of selection. Finally, Chapter 5 describes sample weighting and variance estimation procedures for 2021.The document is available as a PDF.

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